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Mouse Anti-GTF2E1 Recombinant Antibody (CBYJT-1309) (CBMAB-T0325-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to GTF2E1 (General Transcription Factor IIE Subunit 1). The antibody can be used for immunoassay techniques, such as WB, IP, IF, IHC-P, ELISA.
See all GTF2E1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Rat, Mouse
Clone
CBYJT-1309
Antibody Isotype
IgG
Application
WB, IP, IF, IHC-P, ELISA

Basic Information

Immunogen
Amino acids 140-439 mapping at the C-terminus of TFIIE-α of human origin
Specificity
Human, Rat, Mouse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 140-439

Target

Full Name
GTF2E1
Introduction
GTF2E1 recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Entrez Gene ID
Human2960
Mouse74197
Rat303918
UniProt ID
HumanP29083
MouseQ9D0D5
RatG3V992
Alternative Names
FE; TF2E1; TFIIE-A
Function
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Biological Process
Transcription by RNA polymerase II Source: ARUK-UCL
Transcription initiation from RNA polymerase II promoter Source: ProtInc
Transcription open complex formation at RNA polymerase II promoter Source: GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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