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Rabbit Anti-MMP2 Recombinant Antibody (CBFYM-2385) (CBMAB-M2572-FY)

This product is rabbit antibody that recognizes MMP2. The antibody CBFYM-2385 can be used for immunoassay techniques such as: WB, IHC-P.
Host Animal
Rabbit
Application
WB, IHC-P
Immunogen
Recombinant protein
Antibody Isotype
IgG
Cross Reactivity
Human, Mouse, Rat
Clone
CBFYM-2385
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
This gene is a member of the matrix metalloproteinase gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alternative Name
Matrix Metallopeptidase 2; Matrix Metalloproteinase-2; EC 3.4.24.24; CLG4A; MMP-2; TBE-1; Matrix Metalloproteinase 2 (Gelatinase A, 72kDa Gelatinase, 72kDa Type IV Collagenase); Matrix Metallopeptidase 2 (Gelatinase A, 72kDa Gelatinase, 72kDa Type IV Collagenase); Matrix Metalloproteinase-II; 72 KDa Type IV Collagenase
Entrez Gene ID
UniProt ID
Cat CBMAB-M2572-FY
Conjugates
Size
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