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Rabbit Anti-RAMP1 Recombinant Antibody (EPR10867) (CBMAB-1750-CN)

This product is a rabbit antibody that recognizes RAMP1 of human. The antibody EPR10867 can be used for immunoassay techniques such as: FC, WB.
See all RAMP1 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EPR10867
Antibody Isotype
IgG
Application
FC, WB

Basic Information

Immunogen
Synthetic peptide within Human RAMP1 aa 100-200. The exact sequence is proprietary.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
40% Glycerol, 0.05% BSA, 59% PBS
Preservative
0.01% Sodium azide
Concentration
0.6 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
receptor (G protein-coupled) activity modifying protein 1
Introduction
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
Entrez Gene ID
Human10267
Mouse51801
Rat58965
UniProt ID
HumanO60894
MouseQ9WTJ5
RatQ9JJ74
Alternative Names
receptor activity-modifying protein 1; CRLR activity-modifying protein 1; calcitonin receptor-like receptor activity modifying protein 1; receptor (G protein-coupled) activity modifying protein 1; receptor (calcitonin) activity modifying protein 1
Function
Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL.
Biological Process
Biological Process adenylate cyclase-activating G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process amylin receptor signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process angiogenesisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process calcitonin gene-related peptide receptor signaling pathwayManual Assertion Based On ExperimentIPI:UniProtKB
Biological Process calcium ion transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cellular response to hormone stimulusManual Assertion Based On ExperimentIBA:GO_Central
Biological Process G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process intracellular protein transportIEA:InterPro
Biological Process positive regulation of protein glycosylationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process protein localization to plasma membraneManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process protein transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process receptor internalizationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of G protein-coupled receptor signaling pathwayIEA:InterPro
Cellular Location
Membrane
Topology
Extracellular: 27-117
Helical: 118-138
Cytoplasmic: 139-148
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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