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Rabbit Anti-REEP2 Recombinant Antibody (EPR16080) (CBMAB-1759-CN)

This product is a rabbit antibody that recognizes REEP2 of human. The antibody EPR16080 can be used for immunoassay techniques such as: WB.
See all REEP2 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
EPR16080
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Synthetic peptide within Human C5orf19 aa. 150-250.
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
59% PBS, 40% Glycerol, 0.05% BSA
Preservative
0.01% Sodium azide
Concentration
0.844 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Receptor Accessory Protein 2
Introduction
This gene encodes a member of the receptor expression enhancing protein family. Studies of a related gene in mouse suggest that the encoded protein is found in the cell membrane and enhances the function of sweet taste receptors. It is required for endoplasmic reticulum (ER) network formation, shaping and remodeling. The protein may enhance the cell surface expression of odorant receptors.
Entrez Gene ID
51308
UniProt ID
Q9BRK0
Alternative Names
SPG72; Yip2d; C5orf19; SGC32445
Function
Required for endoplasmic reticulum (ER) network formation, shaping and remodeling. May enhance the cell surface expression of odorant receptors (By similarity).
Biological Process
Biological Process endoplasmic reticulum tubular network organizationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein transport into membrane raftIEA:Ensembl
Biological Process regulation of intracellular transportIEA:Ensembl
Biological Process sensory perception of bitter tasteIEA:Ensembl
Biological Process sensory perception of sweet tasteIEA:Ensembl
Cellular Location
Membrane
Involvement in disease
Spastic paraplegia 72 (SPG72):
A form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. SPG72 is a pure form of spastic paraplegia with onset of difficulty walking and stiff legs associated with hyperreflexia and extensor plantar responses in early childhood. Some patients may have pes cavus or sphincter disturbances. Cognition, speech, and ocular function are normal. SPG72 inheritance is autosomal dominant or recessive.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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