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Mouse Anti-SELENOM Recombinant Antibody (CBXS-5000) (CBMAB-S2222-CQ)

This product is a mouse antibody that recognizes SELENOM. The antibody CBXS-5000 can be used for immunoassay techniques such as: ELISA, IP, WB.
See all SELENOM antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-5000
Antibody Isotype
IgG1
Application
ELISA, IP, WB

Basic Information

Immunogen
Purified recombinant human selenoprotein M protein
Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
HEPES, 0.01% BSA, 0.15 M NaCl, 50% glycerol
Preservative
0.03% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Selenoprotein M
Introduction
The protein encoded by this gene belongs to the selenoprotein M/SEP15 family. The exact function of this protein is not known. It is localized in the perinuclear region, is highly expressed in the brain, and may be involved in neurodegenerative disorders. Transgenic mice with targeted deletion of this gene exhibit increased weight gain, suggesting a role for this gene in the regulation of body weight and energy metabolism. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal.
Entrez Gene ID
140606
UniProt ID
Q8WWX9
Alternative Names
Selenoprotein M; SELM; Selenoprotein SelM; SEPM;
Function
May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation.
Biological Process
Biological Process adipose tissue developmentIEA:Ensembl
Biological Process corticosterone secretionIEA:Ensembl
Biological Process hormone metabolic processIEA:Ensembl
Biological Process multicellular organism growthIEA:Ensembl
Biological Process response to selenium ionIEA:Ensembl
Cellular Location
Cytoplasm, perinuclear region
Endoplasmic reticulum
Golgi apparatus
Localized to perinuclear structures corresponding to Golgi and endoplasmic reticulum.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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