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Mouse Anti-SIRPG Recombinant Antibody (CBXS-1865) (CBMAB-S4664-CQ)

This product is a mouse antibody that recognizes SIRPG. The antibody CBXS-1865 can be used for immunoassay techniques such as: WB.
See all SIRPG antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-1865
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
CHO-derived recombinant human SIRP gamma/CD172g, Val64-Ser364, Accession # Q9P1W8
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Concentration
LYOPH
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Signal Regulatory Protein Gamma
Introduction
The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described.
Entrez Gene ID
UniProt ID
Alternative Names
Signal Regulatory Protein Gamma; CD172 Antigen-Like Family Member B; Signal-Regulatory Protein Beta-2; Signal-Regulatory Protein Gamma; CD172g Antigen; SIRP-Gamma; SIRP-B2; SIRPB2;
Function
Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.
Biological Process
Biological Process cell adhesionIEA:UniProtKB-KW
Biological Process cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Biological Process intracellular signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process negative regulation of cell population proliferationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process positive regulation of cell population proliferationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of cell-cell adhesionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of phagocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of T cell activationManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 29-360
Helical: 361-383
Cytoplasmic: 384-387
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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