Sign in or Register   Sign in or Register
  |  

Rabbit Anti-SPTAN1 Recombinant Antibody (EPR3830) (CBMAB-1826-CN)

This product is a rabbit antibody that recognizes SPTAN1 of human. The antibody EPR3830 can be used for immunoassay techniques such as: WB, IP.
See all SPTAN1 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
EPR3830
Antibody Isotype
IgG
Application
WB, IP

Basic Information

Immunogen
Synthetic peptide corresponding to residues in Human Alpha Fodrin
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
49% PBS, 0.05% BSA, 50% Glycerol
Preservative
0.01% Sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Spectrin alpha chain, non-erythrocytic 1
Introduction
This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
Entrez Gene ID
6709
UniProt ID
Q13813
Alternative Names
NEAS; EIEE5; SPTA2
Function
Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
Biological Process
Biological Process actin cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process actin filament cappingIEA:UniProtKB-KW
Cellular Location
Cytoplasm, cytoskeleton
Cytoplasm, cell cortex
Expressed along the cell membrane in podocytes and presumptive tubule cells during glomerulogenesis and is expressed along lateral cell margins in tubule cells.
Involvement in disease
Developmental and epileptic encephalopathy 5 (DEE5):
A disorder characterized by seizures associated with hypsarrhythmia, profound intellectual disability with lack of visual attention and speech development, as well as spastic quadriplegia.
PTM
Phosphorylation of Tyr-1176 decreases sensitivity to cleavage by calpain in vitro.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rabbit Anti-SPTAN1 Recombinant Antibody (EPR3830)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare