Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-TSHZ1 Recombinant Antibody (2F1) (CBMAB-A7945-LY)

Online Inquiry

Summary

Host Animal
Mouse
Specificity
Human
Clone
2F1
Antibody Isotype
IgG2b, κ
Application
WB, ELISA

Basic Information

Immunogen
SDCCAG33 (NP_005777, 619 a.a. ~ 717 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Teashirt Zinc Finger Homeobox 1
Introduction
This gene encodes a colon cancer antigen that was defined by serological analysis of recombinant cDNA expression libraries. The encoded protein is a member of the teashirt C2H2-type zinc-finger protein family and may be involved in transcriptional regulation of developmental processes. [provided by RefSeq]
Entrez Gene ID
UniProt ID
Alternative Names
NY-CO-33; SDCCAG33; TSH1
Function
Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential).
Biological Process
Biological Process anterior/posterior pattern specification Source:Ensembl
Biological Process middle ear morphogenesis Source:Ensembl
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Biological Process soft palate development Source:Ensembl
Cellular Location
Nucleus
Involvement in disease
Aural atresia, congenital (CAA):
A rare anomaly of the ear that involves some degree of failure of the development of the external auditory canal. The malformation can also involve the tympanic membrane, ossicles and middle ear space. The inner ear development is most often normal. Different CAA forms are known. CAA type I is characterized by bony or fibrous atresia of the lateral part of the external auditory canal and an almost normal medial part and middle ear. CAA type II is the most frequent type and is characterized by partial or total aplasia of the external auditory canal. CAA type IIA involves an external auditory canal with either complete bony atresia of the medial part or partial aplasia that ends blindly in a fistula leading to a rudimentary tympanic membrane. CAA type IIB is characterized by bony stenosis of the total length of the external auditory canal. CAA type III involves bony atresia of the external auditory canal and a very small or absent middle-ear cavity.
More Infomation
Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Have you used Mouse Anti-TSHZ1 Recombinant Antibody (2F1)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Online Inquiry