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Mouse Anti-TSHZ1 Recombinant Antibody (CBYJT-5036) (CBMAB-T4611-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TSHZ1 (Teashirt Zinc Finger Homeobox 1). The antibody can be used for immunoassay techniques, such as WB.
See all TSHZ1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-5036
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Human recombinant protein fragment corresponding to amino acids 29-176 of human TSHZ1(NP_005777) produced in E. coli
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.3, 1% BSA, 50% Glycerol
Preservative
0.02% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 29-176

Target

Full Name
Teashirt Zinc Finger Homeobox 1
Introduction
TSHZ1 is a colon cancer antigen that was defined by serological analysis of recombinant cDNA expression libraries. TSHZ1 is a member of the teashirt C2H2-type zinc-finger protein family and may be involved in transcriptional regulation of developmental processes. Mutations in this gene may be associated with congenital aural atresia syndrome.
Entrez Gene ID
10194
UniProt ID
Q6ZSZ6
Alternative Names
Teashirt Zinc Finger Homeobox 1; Serologically Defined Colon Cancer Antigen 33; Antigen NY-CO-33; SDCCAG33; TSH1; Teashirt Family Zinc Finger 1
Function
Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential).
Biological Process
Biological Process anterior/posterior pattern specification Source:Ensembl
Biological Process middle ear morphogenesis Source:Ensembl
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Biological Process soft palate development Source:Ensembl
Cellular Location
Nucleus
Involvement in disease
Aural atresia, congenital (CAA):
A rare anomaly of the ear that involves some degree of failure of the development of the external auditory canal. The malformation can also involve the tympanic membrane, ossicles and middle ear space. The inner ear development is most often normal. Different CAA forms are known. CAA type I is characterized by bony or fibrous atresia of the lateral part of the external auditory canal and an almost normal medial part and middle ear. CAA type II is the most frequent type and is characterized by partial or total aplasia of the external auditory canal. CAA type IIA involves an external auditory canal with either complete bony atresia of the medial part or partial aplasia that ends blindly in a fistula leading to a rudimentary tympanic membrane. CAA type IIB is characterized by bony stenosis of the total length of the external auditory canal. CAA type III involves bony atresia of the external auditory canal and a very small or absent middle-ear cavity.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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