Mouse Anti-TSHZ1 Recombinant Antibody (CBYJT-5037) (CBMAB-T4612-YJ)

Name: Mouse Anti-TSHZ1 Recombinant Antibody (CBYJT-5037)
SKU: CBMAB-T4612-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

CBYJT-5037

Application

Immunogen

Human recombinant protein fragment corresponding to amino acids 29-176 of human TSHZ1(NP_005777) produced in E. coli

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.3, 1% BSA, 50% Glycerol

Preservative

0.02% Sodium Azide

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 29-176

More Infomation

Target

Full Name

Teashirt Zinc Finger Homeobox 1

Introduction

TSHZ1 is a colon cancer antigen that was defined by serological analysis of recombinant cDNA expression libraries. TSHZ1 is a member of the teashirt C2H2-type zinc-finger protein family and may be involved in transcriptional regulation of developmental processes. Mutations in this gene may be associated with congenital aural atresia syndrome.

Entrez Gene ID

10194

UniProt ID

Q6ZSZ6

Alternative Names

Teashirt Zinc Finger Homeobox 1; Serologically Defined Colon Cancer Antigen 33; Antigen NY-CO-33; SDCCAG33; TSH1; Teashirt Family Zinc Finger 1

Function

Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential).

Biological Process

Biological Process anterior/posterior pattern specification Source:Ensembl
Biological Process middle ear morphogenesis Source:Ensembl
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Biological Process soft palate development Source:Ensembl

Cellular Location

Nucleus

Involvement in disease

Aural atresia, congenital (CAA):
A rare anomaly of the ear that involves some degree of failure of the development of the external auditory canal. The malformation can also involve the tympanic membrane, ossicles and middle ear space. The inner ear development is most often normal. Different CAA forms are known. CAA type I is characterized by bony or fibrous atresia of the lateral part of the external auditory canal and an almost normal medial part and middle ear. CAA type II is the most frequent type and is characterized by partial or total aplasia of the external auditory canal. CAA type IIA involves an external auditory canal with either complete bony atresia of the medial part or partial aplasia that ends blindly in a fistula leading to a rudimentary tympanic membrane. CAA type IIB is characterized by bony stenosis of the total length of the external auditory canal. CAA type III involves bony atresia of the external auditory canal and a very small or absent middle-ear cavity.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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