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DDAH1 Matched Antibody Pair (329) (APMAB-329LY)

This antibody pair set can be used for detecting and quantifying protein level of human DDAH1.
See all DDAH1 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-DDAH1 polyclonal antibody, 100 ug
Detection Antibody
Anti-DDAH1 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. [provided by RefSeq, Jul 2008]
Alternative Names
Dimethylarginine Dimethylaminohydrolase 1; Dimethylargininase-1; EC 3.5.3.18; DDAH-1; DDAHI; DDAH;
Entrez Gene ID
UniProt ID

Xie, Z., Hou, L., Shen, S., Wu, Y., Wang, J., Jie, Z., ... & Fan, S. (2022). Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation. Nature communications, 13(1), 1-15.

Kopaliani, I., Jarzebska, N., Billoff, S., Kolouschek, A., Martens-Lobenhoffer, J., Bornstein, S. R., ... & Rodionov, R. N. (2021). Overexpression of dimethylarginine dimethylaminohydrolase 1 protects from angiotensin II-induced cardiac hypertrophy and vascular remodeling. American Journal of Physiology-Heart and Circulatory Physiology, 321(5), H825-H838.

Wang, D., Li, H., Weir, E. K., Xu, Y., Xu, D., & Chen, Y. (2019). Dimethylarginine dimethylaminohydrolase 1 deficiency aggravates monocrotaline-induced pulmonary oxidative stress, pulmonary arterial hypertension and right heart failure in rats. International Journal of Cardiology, 295, 14-20.

Wang, Y., Wang, E., Zhang, Y., Madamsetty, V. S., Ji, B., Radisky, D. C., ... & Mukhopadhyay, D. (2019). Neuropilin‐1 maintains dimethylarginine dimethylaminohydrolase 1 expression in endothelial cells, and contributes to protection from angiotensin II–induced hypertension. The FASEB Journal, 33(1), 494-500.

Reddy, K. R. K., Dasari, C., Duscharla, D., Supriya, B., Ram, N. S., Surekha, M. V., ... & Ummanni, R. (2018). Dimethylarginine dimethylaminohydrolase-1 (DDAH1) is frequently upregulated in prostate cancer, and its overexpression conveys tumor growth and angiogenesis by metabolizing asymmetric dimethylarginine (ADMA). Angiogenesis, 21(1), 79-94.

Buijs, N., Oosterink, J. E., Jessup, M., Schierbeek, H., Stolz, D. B., Houdijk, A. P., ... & van Leeuwen, P. A. (2017). A new key player in VEGF-dependent angiogenesis in human hepatocellular carcinoma: dimethylarginine dimethylaminohydrolase 1. Angiogenesis, 20(4), 557-565.

Xu, X., Zhang, P., Kwak, D., Fassett, J., Yue, W., Atzler, D., ... & Chen, Y. (2017). Cardiomyocyte dimethylarginine dimethylaminohydrolase-1 (DDAH1) plays an important role in attenuating ventricular hypertrophy and dysfunction. Basic research in cardiology, 112(5), 1-11.

Hulin, J. A., Tommasi, S., Elliot, D., Hu, D. G., Lewis, B. C., & Mangoni, A. A. (2017). MiR-193b regulates breast cancer cell migration and vasculogenic mimicry by targeting dimethylarginine dimethylaminohydrolase 1. Scientific reports, 7(1), 1-15.

Li, T., Feng, R., Zhao, C., Wang, Y., Wang, J., Liu, S., ... & Lu, Z. (2017). Dimethylarginine dimethylaminohydrolase 1 protects against high-fat diet-induced hepatic steatosis and insulin resistance in mice. Antioxidants & Redox Signaling, 26(11), 598-609.

Shi, L., Zhao, C., Wang, H., Lei, T., Liu, S., Cao, J., & Lu, Z. (2017). Dimethylarginine dimethylaminohydrolase 1 deficiency induces the epithelial to mesenchymal transition in renal proximal tubular epithelial cells and exacerbates kidney damage in aged and diabetic mice. Antioxidants & Redox Signaling, 27(16), 1347-1360.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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