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AASDHPPT

The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia. [provided by RefSeq, Jul 2008]

Full Name

Aminoadipate-Semialdehyde Dehydrogenase-Phosphopantetheinyl Transferase

Function

Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'-phosphopantetheine moiety from coenzyme A, regardless of whether the CoA is presented in the free thiol form or as an acetyl thioester, to a serine residue of a broad range of acceptors including the acyl carrier domain of FASN.

Biological Process

Lysine biosynthetic process via aminoadipic acid
Pantothenate metabolic process

Cellular Location

Cytosol

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Anti-AASDHPPT antibodies

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Mouse Anti-AASDHPPT Recombinant Antibody (V2-610865) (CBMAB-A0008-LY)

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Target: AASDHPPT

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: V2-610865

Application*: WB, E

Rabbit Anti-AASDHPPT Recombinant Antibody (V2-639278) (CBMAB-EN005-LY)

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Target: AASDHPPT

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: V2-639278

Application*: WB: 1:500~1:1000 ELISA: 1:40000

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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