Rabbit Anti-AASDHPPT Recombinant Antibody (V2-639278) (CBMAB-EN005-LY)

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Basic Information

Host Animal
Rabbit
Clone
V2-639278
Application
WB: 1:500~1:1000 ELISA: 1:40000
Immunogen
The antibody was produced against synthesized peptide derived from internal of human AASDHPPT.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
Aminoadipate-Semialdehyde Dehydrogenase-Phosphopantetheinyl Transferase
Introduction
The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia. [provided by RefSeq, Jul 2008]
Entrez Gene ID
Human60496
Mouse67618
Rat300328
UniProt ID
HumanQ9NRN7
MouseQ9CQF6
RatB2RYJ4
Alternative Names
Aminoadipate-Semialdehyde Dehydrogenase-Phosphopantetheinyl Transferase; Alpha-Aminoadipic Semialdehyde Dehydrogenase-Phosphopantetheinyl Transferase; Holo-[Acyl-Carrier-Protein] Synthase; 4-Phosphopantetheinyl Transferase; Holo ACP Synthase; LYS5 Ortholog; AASD-PPT; L-Aminoadipate-Semialdehyde Dehydrogenase-Phosphopantetheinyl Transferase;
Function
Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'-phosphopantetheine moiety from coenzyme A, regardless of whether the CoA is presented in the free thiol form or as an acetyl thioester, to a serine residue of a broad range of acceptors including the acyl carrier domain of FASN.
Biological Process
Lysine biosynthetic process via aminoadipic acid
Pantothenate metabolic process
Cellular Location
Cytosol
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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