C2

Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined
Full Name
complement C2

Anti-C2 antibodies

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Rabbit Anti-C2 Recombinant Antibody (2) (CBMAB-C4297-LY)

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Target: C2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 2
Application*: E
Datasheet SDS

Mouse Anti-C2 Recombinant Antibody (06) (CBMAB-C1806-LY)

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Target: C2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 06
Application*: E
Datasheet SDS

Rabbit Anti-C2 Recombinant Antibody (014) (CBMAB-C1622-LY)

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Target: C2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 014
Application*: E
Datasheet SDS

Mouse Anti-C2 Recombinant Antibody (269716) (CBMAB-C0767-LY)

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Target: C2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 269716
Application*: WB, IP
Datasheet SDS

Mouse Anti-C2 Recombinant Antibody (CBFYC-0617) (CBMAB-C0671-FY)

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Target: C2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-0617
Application*: WB, IP, IF, E, P
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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