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CEBPD

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11. [provided by RefSeq, Sep 2010]

Full Name

CCAAT/Enhancer Binding Protein Delta

Function

Transcription activator that recognizes two different DNA motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers (PubMed:16397300).
Important transcription factor regulating the expression of genes involved in immune and inflammatory responses (PubMed:1741402, PubMed:16397300).
Transcriptional activator that enhances IL6 transcription alone and as heterodimer with CEBPB (PubMed:1741402).

Biological Process

Cytokine-mediated signaling pathway Source: Reactome
Regulation of cell differentiation Source: GO_Central
Regulation of transcription by RNA polymerase II Source: GO_Central
Transcription by RNA polymerase II Source: ProtInc
Viral life cycle Source: Reactome

Cellular Location

Nucleus

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Anti-CEBPD antibodies

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Rabbit Anti-CEBPD Recombinant Antibody (CBWJC-2462) (CBMAB-C3530WJ)

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Target: CEBPD

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse

Clone: CBWJC-2462

Application*: WB

Mouse Anti-CEBPD Recombinant Antibody (CBXC-1726) (CBMAB-C5101-CQ)

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Target: CEBPD

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBXC-1726

Application*: WB, IP, IF, E

Mouse Anti-CEBPD Recombinant Antibody (CBXC-1705) (CBMAB-C3007-CQ)

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Target: CEBPD

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat

Clone: CBXC-1705

Application*: WB, IP, IF, E

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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