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CPB2

CPB2 (Carboxypeptidase B2) is a Protein Coding gene. Diseases associated with CPB2 include Factor Xiii Deficiency and Factor Xi Deficiency. Among its related pathways are Peptide hormone metabolism and Complement and coagulation cascades. Gene Ontology (GO) annotations related to this gene include metallocarboxypeptidase activity and carboxypeptidase activity. An important paralog of this gene is CPB1.
Full Name
Carboxypeptidase B2
Function
Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.
Biological Process
Blood coagulation Source: UniProtKB-KW
Cellular response to glucose stimulus Source: Ensembl
Fibrinolysis Source: GO_Central
Liver regeneration Source: Ensembl
Negative regulation of fibrinolysis Source: Ensembl
Negative regulation of hepatocyte proliferation Source: Ensembl
Negative regulation of plasminogen activation Source: Ensembl
Positive regulation of extracellular matrix constituent secretion Source: Ensembl
Proteolysis Source: GO_Central
Regulation of complement activation Source: Reactome
Response to drug Source: Ensembl
Response to heat Source: Ensembl
Cellular Location
Secreted
PTM
N-glycosylated. N-glycan at Asn-108: Hex5HexNAc4.

Anti-CPB2 antibodies

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Mouse Anti-CPB2 Recombinant Antibody (CBWJC-3010) (CBMAB-C4165WJ)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-3010
Application*: E, WB

Mouse Anti-CPB2 Recombinant Antibody (CBWJC-3009) (CBMAB-C4164WJ)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBWJC-3009
Application*: E, WB

Mouse Anti-CPB2 Recombinant Antibody (CBWJC-3007) (CBMAB-C4162WJ)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBWJC-3007
Application*: E, WB

Mouse Anti-CPB2 Recombinant Antibody (CBWJC-3006) (CBMAB-C4161WJ)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-3006
Application*: IH

Rabbit Anti-CPB2 Recombinant Antibody (173) (CBMAB-C3414-LY)

Datasheet SDS
Target: CPB2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 173
Application*: E

Mouse Anti-CPB2 Recombinant Antibody (CBFYC-0278) (CBMAB-C0308-FY)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0278
Application*: SE

Mouse Anti-CPB2 Recombinant Antibody (CBFYC-0280) (CBMAB-C0310-FY)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0280
Application*: WB, E, SE

Rabbit Anti-CPB2 Recombinant Antibody (CBFYC-2151) (CBMAB-C2219-FY)

Datasheet SDS
Target: CPB2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYC-2151
Application*: E

Mouse Anti-CPB2 Recombinant Antibody (CBFYC-2152) (CBMAB-C2220-FY)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2152
Application*: E, WB

Mouse Anti-CPB2 Recombinant Antibody (CBFYC-2154) (CBMAB-C2222-FY)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-2154
Application*: E, WB

Mouse Anti-CPB2 Recombinant Antibody (CBFYC-2155) (CBMAB-C2223-FY)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-2155
Application*: E

Mouse Anti-CPB2 Recombinant Antibody (CBXC-2412) (CBMAB-C0025-CQ)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2412
Application*: WB, E

Mouse Anti-CPB2 Recombinant Antibody (CBWJC-3005) (CBMAB-C4160WJ)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human
Clone: CBWJC-3005
Application*: E

Mouse Anti-CPB2 Recombinant Antibody (13D5) (CBMAB-C0315-LY)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13D5
Application*: SE

Mouse Anti-CPB2 Recombinant Antibody (15A10) (CBMAB-C3228-LY)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 15A10
Application*: E, WB

Mouse Anti-CPB2 Recombinant Antibody (16C5) (CBMAB-C3358-LY)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 16C5
Application*: E, WB

Mouse Anti-CPB2 Recombinant Antibody (3D5) (CBMAB-C5881-LY)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3D5
Application*: P

Mouse Anti-CPB2 Recombinant Antibody (5024) (CBMAB-C7134-LY)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5024
Application*: E, I, WB

Mouse Anti-CPB2 Recombinant Antibody (5065) (CBMAB-C7138-LY)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human
Clone: 5065
Application*: E

Mouse Anti-CPB2 Recombinant Antibody (5081) (CBMAB-C7139-LY)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 5081
Application*: E, WB

Mouse Anti-CPB2 Recombinant Antibody (650801) (CBMAB-C7919-LY)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 650801
Application*: WB, IP

Mouse Anti-CPB2 Recombinant Antibody (7E134) (CBMAB-C8661-LY)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7E134
Application*: E, WB

Mouse Anti-CPB2 Recombinant Antibody (CBYY-C2923) (CBMAB-C4366-YY)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2923
Application*: WB, IP

Rabbit Anti-CPB2 Recombinant Antibody (CBLC176-LY) (CBMAB-C11134-LY)

Datasheet SDS
Target: CPB2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBLC176-LY
Application*: E

Rabbit Anti-CPB2 Recombinant Antibody (EG800) (CBMAB-EN956-LY)

Datasheet SDS
Target: CPB2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG800
Application*: WB: 1:500~1:1000 ELISA: 1:40000

Mouse Anti-CPB2 Recombinant Antibody (CBYJT-1142) (CBMAB-T0155-YJ)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1142
Application*: E, WB

Mouse Anti-CPB2 Recombinant Antibody (CBYJT-1143) (CBMAB-T0156-YJ)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1143
Application*: E, WB

Mouse Anti-CPB2 Recombinant Antibody (CBYJT-1145) (CBMAB-T0158-YJ)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJT-1145
Application*: E, WB

Mouse Anti-CPB2 Recombinant Antibody (CBYJT-1148) (CBMAB-T0161-YJ)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1148
Application*: E, WB

Mouse Anti-CPB2 Recombinant Antibody (CBXC-2408) (CBMAB-C0023-CQ)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2408
Application*: E

Mouse Anti-CPB2 Recombinant Antibody (13H4) (CBMAB-C0319-LY)

Datasheet SDS
Target: CPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13H4
Application*: WB, SE
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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