CSNK2B

CSNK2B (Casein Kinase 2 Beta) is a Protein Coding gene. Diseases associated with CSNK2B include Autosomal Dominant Non-Syndromic Intellectual Disability and Egg Allergy. Among its related pathways are Mitotic Prometaphase and Mitophagy - animal. Gene Ontology (GO) annotations related to this gene include identical protein binding and receptor binding.

Casein Kinase 2 Beta

Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (PubMed:11239457, PubMed:16818610).

Participates in Wnt signaling (By similarity).

Adiponectin-activated signaling pathway Source: BHF-UCL
Cellular protein-containing complex assembly Source: BHF-UCL
Endothelial tube morphogenesis Source: BHF-UCL
Macroautophagy Source: Reactome
Mitotic chromosome condensation Source: Reactome
Negative regulation of blood vessel endothelial cell migration Source: BHF-UCL
Negative regulation of cell population proliferation Source: BHF-UCL
Neutrophil degranulation Source: Reactome
Peptidyl-threonine phosphorylation Source: CAFA
Phosphatidylcholine biosynthetic process Source: Reactome
Positive regulation of activin receptor signaling pathway Source: BHF-UCL
Positive regulation of pathway-restricted SMAD protein phosphorylation Source: BHF-UCL
Protein folding Source: Reactome
Regulation of DNA binding Source: BHF-UCL
Regulation of signal transduction by p53 class mediator Source: Reactome
Signal transduction Source: UniProtKB
Wnt signaling pathway Source: UniProtKB-KW

Cytosol; Extracellular exosome; Extracellular region; Nucleoplasm; Nucleus; Cytoplasm; Ficolin-1-rich granule lumen; Protein kinase CK2 complex; Secretory granule lumen

Poirier-Bienvenu neurodevelopmental syndrome (POBINDS):
An autosomal dominant neurodevelopmental disorder characterized by onset of seizures in infancy, developmental delay, impaired intellectual development, and poor or absent speech.

Phosphorylated by alpha subunit.