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CSTB

CSTB (Cystatin B) is a Protein Coding gene. Diseases associated with CSTB include Myoclonic Epilepsy Of Unverricht And Lundborg and Unverricht-Lundborg Syndrome. Among its related pathways are Innate Immune System. Gene Ontology (GO) annotations related to this gene include endopeptidase inhibitor activity. An important paralog of this gene is CSTA.
Full Name
Cystatin B
Function
This is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B.
Biological Process
Adult locomotory behavior Source: Ensembl
Negative regulation of peptidase activity Source: BHF-UCL
Negative regulation of proteolysis Source: UniProtKB
Neutrophil degranulation Source: Reactome
Cellular Location
Cytoplasm; Nucleus
Involvement in disease
Epilepsy, progressive myoclonic 1 (EPM1):
A form of progressive myoclonic epilepsy, a clinically and genetically heterogeneous group of disorders defined by the combination of action and reflex myoclonus, other types of epileptic seizures, and progressive neurodegeneration and neurocognitive impairment. EPM1 is an autosomal recessive form characterized by severe, stimulus-sensitive myoclonus and tonic-clonic seizures. The onset, occurring between 6 and 13 years of age, is characterized by convulsions. Myoclonus begins 1 to 5 years later. The twitchings occur predominantly in the proximal muscles of the extremities and are bilaterally symmetrical, although asynchronous. At first small, they become late in the clinical course so violent that the victim is thrown to the floor. Mental deterioration and eventually dementia develop.

Anti-CSTB antibodies

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Mouse Anti-CSTB Antibody (5BA11) (CBMAB-1100CQ)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5BA11
Application*: E, WB

Mouse Anti-CSTB Recombinant Antibody (M2F1) (CBMAB-C4475WJ)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: M2F1
Application*: E, IF, P, WB

Mouse Anti-CSTB Recombinant Antibody (CBXS-2395) (CBMAB-S5153-CQ)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-2395
Application*: E, WB

Rabbit Anti-CSTB Recombinant Antibody (CBXS-1503) (CBMAB-S4356-CQ)

Datasheet SDS
Target: CSTB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Rat, Human
Clone: CBXS-1503
Application*: WB, P, F

Rabbit Anti-CSTB Recombinant Antibody (CBXS-1502) (CBMAB-S4355-CQ)

Datasheet SDS
Target: CSTB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-1502
Application*: WB, IC

Mouse Anti-CSTB Recombinant Antibody (CBXS-5510) (CBMAB-S2718-CQ)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-5510
Application*: E, IF, IH, WB

Mouse Anti-CSTB Recombinant Antibody (CBXS-5502) (CBMAB-S2711-CQ)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-5502
Application*: E, IH, WB

Mouse Anti-CSTB Recombinant Antibody (CBXS-4564) (CBMAB-S1804-CQ)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-4564
Application*: WB, E

Mouse Anti-CSTB Recombinant Antibody (CBXC-0599) (CBMAB-C3945-CQ)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXC-0599
Application*: E, IF, P, WB

Mouse Anti-CSTB Recombinant Antibody (CBXC-0598) (CBMAB-C3944-CQ)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXC-0598
Application*: E, P, WB

Mouse Anti-CSTB Recombinant Antibody (CBXC-1024) (CBMAB-C3943-CQ)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-1024
Application*: WB, IP, N

Mouse Anti-CSTB Recombinant Antibody (CBXC-0600) (CBMAB-C3942-CQ)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0600
Application*: WB, IH

Mouse Anti-CSTB Recombinant Antibody (M1-C1) (CBMAB-C3941-CQ)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: M1-C1
Application*: E, WB, IH

Mouse Anti-CSTB Recombinant Antibody (CBXC-2106) (CBMAB-C0138-CQ)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-2106
Application*: WB, E

Mouse Anti-CSTB Recombinant Antibody (CBFYC-2363) (CBMAB-C2435-FY)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-2363
Application*: E

Rat Anti-CSTB Recombinant Antibody (CBFYC-2361) (CBMAB-C2433-FY)

Datasheet SDS
Target: CSTB
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYC-2361
Application*: WB, IP

Rat Anti-CSTB Recombinant Antibody (CBFYC-2360) (CBMAB-C2432-FY)

Datasheet SDS
Target: CSTB
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYC-2360
Application*: IH

Mouse Anti-CSTB Recombinant Antibody (2F1) (CBMAB-1460-CN)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2F1
Application*: WB, E

Rat Anti-CSTB Recombinant Antibody (CBFYC-2357) (CBMAB-C2429-FY)

Datasheet SDS
Target: CSTB
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBFYC-2357
Application*: IH, WB

Mouse Anti-CSTB Recombinant Antibody (CBFYC-2358) (CBMAB-C2430-FY)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBFYC-2358
Application*: N, WB

Mouse Anti-CSTB Recombinant Antibody (CBFYC-2359) (CBMAB-C2431-FY)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2359
Application*: IH, WB

Rat Anti-CSTB Recombinant Antibody (227807) (CBMAB-C0680-LY)

Datasheet SDS
Target: CSTB
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 227807
Application*: IH

Mouse Anti-CSTB Recombinant Antibody (06) (CBMAB-C1816-LY)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 06
Application*: E

Mouse Anti-CSTB Recombinant Antibody (13A250) (CBMAB-C2751-LY)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13A250
Application*: C, WB

Mouse Anti-CSTB Recombinant Antibody (14L336) (CBMAB-C3174-LY)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 14L336
Application*: N, WB

Rat Anti-CSTB Recombinant Antibody (14L337) (CBMAB-C3175-LY)

Datasheet SDS
Target: CSTB
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 14L337
Application*: C, WB

Mouse Anti-CSTB Recombinant Antibody (RJMW-2E7) (CBMAB-S6498-CQ)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: RJMW-2E7
Application*: WB, IP, E, IC

Rat Anti-CSTB Recombinant Antibody (227818) (CBMAB-C4424-LY)

Datasheet SDS
Target: CSTB
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 227818
Application*: WB, IP

Mouse Anti-CSTB Recombinant Antibody (CBYY-C2916) (CBMAB-C4359-YY)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C2916
Application*: E, WB

Mouse Anti-CSTB Recombinant Antibody (8k275) (CBMAB-C0423-CN)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 8k275
Application*: E, WB

Mouse Anti-CSTB Recombinant Antibody (M2-F1) (CBMAB-C3022-CN)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: M2-F1
Application*: E, IF, IH, WB

Mouse Anti-CSTB Recombinant Antibody (CBCNC-435) (CBMAB-C3023-CN)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBCNC-435
Application*: E, WB

Mouse Anti-CSTB Recombinant Antibody (CBCNC-436) (CBMAB-C3024-CN)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBCNC-436
Application*: E, WB

Mouse Anti-CSTB Recombinant Antibody (CBCNC-437) (CBMAB-C3025-CN)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBCNC-437
Application*: E, WB, P

Mouse Anti-CSTB Recombinant Antibody (CBCNC-438) (CBMAB-C3026-CN)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBCNC-438
Application*: E, WB, P, IF

Mouse Anti-CSTB Recombinant Antibody (CBCNC-440) (CBMAB-C3028-CN)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBCNC-440
Application*: E, WB, IH

Rat Anti-CSTB Recombinant Antibody (RM0215-45N2) (CBMAB-C11269-LY)

Datasheet SDS
Target: CSTB
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: RM0215-45N2
Application*: IH, WB

Mouse Anti-CSTB Recombinant Antibody (RJMW 2E7) (CBMAB-C11268-LY)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: RJMW 2E7
Application*: WB, IP, IF

Mouse Anti-CSTB Recombinant Antibody (2B6) (CBMAB-BR146LY)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2B6
Application*: FC

Mouse Anti-CSTB Recombinant Antibody (CBMAB-BR147LY)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Application*: FC

Mouse Anti-CSTB Recombinant Antibody (CAP584) (CBMAB-AP1750LY)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CAP584
Application*: ICC, IHC, IP, WB

Mouse Anti-CSTB Recombinant Antibody (CAP585) (CBMAB-AP1751LY)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CAP585
Application*: ICC, IHC, IP, WB

Mouse Anti-CSTB Recombinant Antibody (CAP586) (CBMAB-AP1752LY)

Datasheet SDS
Target: CSTB
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CAP586
Application*: ICC, IHC, IP, WB

CSTB Matched Antibody Pair (307) (APMAB-307LY)

Datasheet SDS
Target: CSTB
Specificity: Human

CSTB Matched Antibody Pair (306) (APMAB-306LY)

Datasheet SDS
Target: CSTB
Specificity: Human
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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