CTNNBIP1

The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]

catenin, beta interacting protein 1

Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway.

Anterior/posterior pattern specification Source: Ensembl
Branching involved in ureteric bud morphogenesis Source: Ensembl
Negative regulation of DNA binding Source: Ensembl
Negative regulation of DNA-binding transcription factor activity Source: BHF-UCL
Negative regulation of mesenchymal cell proliferation Source: BHF-UCL
Negative regulation of protein binding Source: BHF-UCL
Negative regulation of protein-containing complex assembly Source: Ensembl
Negative regulation of smooth muscle cell proliferation Source: Ensembl
Negative regulation of transcription initiation from RNA polymerase II promoter Source: Ensembl
Negative regulation of Wnt signaling pathway Source: GO_Central
Positive regulation of monocyte differentiation Source: BHF-UCL
Positive regulation of osteoblast differentiation Source: BHF-UCL
Regulation of vascular permeability involved in acute inflammatory response Source: BHF-UCL
Wnt signaling pathway Source: UniProtKB-KW

Cytoplasm; Nucleus