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CTNNBIP1

The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]

Full Name

catenin, beta interacting protein 1

Function

Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway.

Biological Process

Anterior/posterior pattern specification Source: Ensembl
Branching involved in ureteric bud morphogenesis Source: Ensembl
Negative regulation of DNA binding Source: Ensembl
Negative regulation of DNA-binding transcription factor activity Source: BHF-UCL
Negative regulation of mesenchymal cell proliferation Source: BHF-UCL
Negative regulation of protein binding Source: BHF-UCL
Negative regulation of protein-containing complex assembly Source: Ensembl
Negative regulation of smooth muscle cell proliferation Source: Ensembl
Negative regulation of transcription initiation from RNA polymerase II promoter Source: Ensembl
Negative regulation of Wnt signaling pathway Source: GO_Central
Positive regulation of monocyte differentiation Source: BHF-UCL
Positive regulation of osteoblast differentiation Source: BHF-UCL
Regulation of vascular permeability involved in acute inflammatory response Source: BHF-UCL
Wnt signaling pathway Source: UniProtKB-KW

Cellular Location

Cytoplasm; Nucleus

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Anti-CTNNBIP1 antibodies

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Rabbit Anti-CTNNBIP1 Recombinant Antibody (CBXC-0614) (CBMAB-C3118-CQ)

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Target: CTNNBIP1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBXC-0614

Application*: F, WB, P

Mouse Anti-CTNNBIP1 Recombinant Antibody (3B3) (V2LY-0125-LY330)

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Target: CTNNBIP1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 3B3

Application*: WB, E

Mouse Anti-CTNNBIP1 Recombinant Antibody (CBCNC-097) (V2LY-0125-LY329)

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Target: CTNNBIP1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBCNC-097

Application*: WB, IF, IH

Mouse Anti-CTNNBIP1 Recombinant Antibody (5C6) (V2LY-0125-LY327)

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Target: CTNNBIP1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat

Clone: 5C6

Application*: E, WB, IP

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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