CTNNBL1

The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome.
Full Name
CTNNBL1
Function
Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis.
Biological Process
Apoptotic process Source: UniProtKB-KW
mRNA splicing, via spliceosome Source: Reactome
Positive regulation of apoptotic process Source: UniProtKB
Somatic diversification of immunoglobulins Source: UniProtKB
Cellular Location
Isoform 1: Nucleus
Isoform 2: Cytoplasm
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Anti-CTNNBL1 antibodies

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Mouse Anti-CTNNBL1 Recombinant Antibody (C7532) (CBMAB-C7532-LY)

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Target: CTNNBL1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: C7532
Application*: E, F, WB
Datasheet SDS

Mouse Anti-CTNNBL1 Recombinant Antibody (1E4F5) (CBMAB-C3955-LY)

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Target: CTNNBL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1E4F5
Application*: WB, P, IF, E, F
Datasheet SDS

Mouse Anti-CTNNBL1 Recombinant Antibody (CBT3761) (V2LY-0625-LY195)

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Target: CTNNBL1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBT3761
Application*: F
Datasheet SDS

Mouse Anti-CTNNBL1 Recombinant Antibody (CBT4520) (V2LY-0625-LY150)

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Target: CTNNBL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4520
Application*: WB, IH, IC, F
Datasheet SDS

Mouse Anti-CTNNBL1 Recombinant Antibody (CBT3665) (V2LY-0625-LY1197)

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Target: CTNNBL1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBT3665
Application*: WB, IH, IC, F
Datasheet SDS

Mouse Anti-CTNNBL1 Recombinant Antibody (CBFYC-2413) (V2LY-0125-LY336)

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Target: CTNNBL1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat, Dog
Clone: CBFYC-2413
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-CTNNBL1 Recombinant Antibody (C5244) (V2LY-0125-LY334)

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Target: CTNNBL1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: C5244
Application*: WB, P, IF, E, F
Datasheet SDS

Mouse Anti-CTNNBL1 Recombinant Antibody (C0672) (V2LY-0125-LY332)

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Target: CTNNBL1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat, Dog
Clone: C0672
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-CTNNBL1 Recombinant Antibody (1103CQ) (V2LY-0125-LY331)

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Target: CTNNBL1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat, Dog
Clone: 1103CQ
Application*: WB, IP, IF, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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