DUSP14

In addition to antigen recognition by the T-cell receptor, T-cell activation requires a second signal from a costimulatory receptor, such as CD28 (MIM 186760), which interacts with B7-1 (CD80; MIM 112203) and B7-2 (CD86; MIM 601020) ligands on antigen-presenting cells. CD28 costimulation induces transcription of interleukin-2 (IL2; MIM 147680) and stabilizes newly synthesized IL2 through the activation of mitogen-activated protein kinases (MAPKs), such as ERK (e.g., MAP2K4; MIM 601335) and JNK (see MIM 601158), and the subsequent creation of AP1 transcription factor (see MIM 165160). DUSP14 is a negative regulator of CD28 signaling.[supplied by OMIM
Full Name
dual specificity phosphatase 14
Research Area
Involved in the inactivation of MAP kinases. Dephosphorylates ERK, JNK and p38 MAP-kinases.

Anti-DUSP14 antibodies

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Mouse Anti-DUSP14 Recombinant Antibody (4B5-E6) (CBMAB-D1884-YC)

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Target: DUSP14
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4B5-E6
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-DUSP14 Recombinant Antibody (4F6) (CBMAB-D1883-YC)

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Target: DUSP14
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 4F6
Application*: E
Datasheet SDS

Human Recombinant DUSP14 protein, His & MBP Tag (V2LY-0526-LY3657)

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Target: DUSP14
Expressed Host: E. coli
Sequence: Amino Acid: 1-191
Tag: His & MBP Tag
Datasheet SDS

Mouse Anti-DUSP14 Recombinant Antibody (4B5-E6) (V2LY-0425-LY1060)

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Target: DUSP14
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4B5-E6
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-DUSP14 Recombinant Antibody (4F6) (V2LY-0425-LY1059)

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Target: DUSP14
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: 4F6
Application*: E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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