EMCN
EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.
Full Name
ENDOMUCIN
Research Area
Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.
Biological Process
Hematopoietic stem cell homeostasis Source: Ensembl
Cellular Location
Isoform 1: Cell membrane; Membrane. Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.
Isoform 2: Secreted
Isoform 2: Secreted
Topology
Extracellular: 19-190
Helical: 191-211
Cytoplasmic: 212-261
Helical: 191-211
Cytoplasmic: 212-261
PTM
Highly O-glycosylated. Sialic acid-rich glycoprotein.
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Anti-EMCN antibodies
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Target: EMCN
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: 28
Application*: WB, IP, IF, P, F
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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