FAM3B

FAM3B (Family With Sequence Similarity 3 Member B) is a Protein Coding gene. Diseases associated with FAM3B include Reticulate Acropigmentation Of Kitamura. Gene Ontology (GO) annotations related to this gene include cytokine activity. An important paralog of this gene is FAM3C.
Full Name
family with sequence similarity 3, member B
Research Area
Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner.
Biological Process
Apoptotic process Source: UniProtKB-KW
Glucose homeostasis Source: InterPro
Insulin secretion Source: UniProtKB
Cellular Location
Secreted. Present in insulin secretory granules and likely cosecreted with insulin. Localized in discrete vesicular and perinuclear structure.
PTM
2 N-termini have been observed in the mature protein: the first at Glu-30, resulting from signal peptide cleavage, the second at Ser-46.
O-glycosylated.By similarity
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Anti-FAM3B antibodies

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Target: FAM3B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1E7
Application*: WB, E, IP, IH
Target: FAM3B
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-1721
Application*: WB
Target: FAM3B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-2564
Application*: WB, IP, IF, E, P
More Infomation
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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