FAM3B

FAM3B (Family With Sequence Similarity 3 Member B) is a Protein Coding gene. Diseases associated with FAM3B include Reticulate Acropigmentation Of Kitamura. Gene Ontology (GO) annotations related to this gene include cytokine activity. An important paralog of this gene is FAM3C.

Full Name

family with sequence similarity 3, member B

Research Area

Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner.

Biological Process

Apoptotic process Source: UniProtKB-KW
Glucose homeostasis Source: InterPro
Insulin secretion Source: UniProtKB

Cellular Location

Secreted. Present in insulin secretory granules and likely cosecreted with insulin. Localized in discrete vesicular and perinuclear structure.

PTM

2 N-termini have been observed in the mature protein: the first at Glu-30, resulting from signal peptide cleavage, the second at Ser-46.
O-glycosylated.By similarity

Anti-FAM3B antibodies

Mouse Anti-FAM3B Recombinant Antibody (CBXF-1721) (CBMAB-F3256-CQ)

Datasheet

SDS

Target: FAM3B

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBXF-1721

Application*: WB, IP, IF, P, E

Mouse Anti-FAM3B Recombinant Antibody (CBXF-2564) (CBMAB-F3013-CQ)

Datasheet

SDS

Target: FAM3B

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXF-2564

Application*: WB

Mouse Anti-FAM3B Recombinant Antibody (1E7) (CBMAB-A2820-LY)

Datasheet

SDS

Target: FAM3B

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 1E7

Application*: WB, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)