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FCN2

The product of this gene belongs to the ficolin family of proteins. This family is characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. This gene is predominantly expressed in the liver, and has been shown to have carbohydrate binding and opsonic activities. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Full Name
Ficolin 2
Research Area
May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region.
Biological Process
Complement activation, lectin pathway Source: UniProtKB
Defense response to Gram-negative bacterium Source: UniProtKB
Defense response to Gram-positive bacterium Source: UniProtKB
Opsonization Source: UniProtKB
Recognition of apoptotic cell Source: UniProtKB
Cellular Location
Secreted
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Anti-FCN2 antibodies

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Mouse Anti-FCN2 Recombinant Antibody (CBXF-1561) (CBMAB-F4038-CQ)

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Target: FCN2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-1561
Application*: E, WB
Datasheet SDS

Mouse Anti-FCN2 Recombinant Antibody (CBYJL-028) (CBMAB-L0057-YJ)

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Target: FCN2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-028
Application*: E, WB
Datasheet SDS

Mouse Anti-FCN2 Recombinant Antibody (CBYJL-027) (CBMAB-L0056-YJ)

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Target: FCN2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJL-027
Application*: E, WB
Datasheet SDS

Mouse Anti-FCN2 Recombinant Antibody (NA) (CBMAB-AO457LY)

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Target: FCN2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: NA
Application*: ELISA, WB
Datasheet SDS

Recombinant Mouse Anti-Fcn2 Antibody (CBHb176) (CBMAB-Hb485-LY)

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Target: FCN2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: CBHb176
Application*: IHC-F, Immuno assays, IP, WB
Datasheet SDS

Mouse Anti-FCN2 Recombinant Antibody (GN4) (CBMAB-X0161-FY)

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Target: FCN2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: GN4
Application*: C, IA, IP
Datasheet SDS

Mouse Anti-FCN2 Recombinant Antibody (CBXF-2935) (CBMAB-F3642-CQ)

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Target: FCN2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-2935
Application*: E, WB
Datasheet SDS

Mouse Anti-FCN2 Recombinant Antibody (CBXF-2934) (CBMAB-F3641-CQ)

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Target: FCN2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-2934
Application*: E, WB
Datasheet SDS

Mouse Anti-FCN2 Recombinant Antibody (CBXF-2592) (CBMAB-F3028-CQ)

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Target: FCN2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-2592
Application*: WB
Datasheet SDS

Mouse Anti-FCN2 Recombinant Antibody (GN5) (CBMAB-F2570-CQ)

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Target: FCN2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: GN5
Application*: IP, WB
Datasheet SDS

Mouse Anti-FCN2 Recombinant Antibody (CBXF-3734) (CBMAB-F1035-CQ)

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Target: FCN2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXF-3734
Application*: WB, IP, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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