FCRL2

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Full Name
Fc Receptor Like 2
Research Area
May have an regulatory role in normal and neoplastic B cell development.
Biological Process
Cell-cell signaling Source: UniProtKB
Cell surface receptor signaling pathway Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 20-401
Helical: 402-422
Cytoplasmic: 423-508
PTM
Isoform 2 is N- and O-glycosylated, and phosphorylated.
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Anti-FCRL2 antibodies

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Human Recombinant FCRL2 protein, His Tag (V2LY-0526-LY4041)

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Target: FCRL2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-395
Tag: His Tag
Datasheet SDS

Mouse Anti-FCRL2 Recombinant Antibody (CBXC-0859) (V2LY-0925-LY1111)

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Target: FCRL2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXC-0859
Application*: F
Datasheet SDS

Mouse Anti-FCRL2 Recombinant Antibody (CBXF-1137) (V2LY-0925-LY1110)

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Target: FCRL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-1137
Application*: WB, F
Datasheet SDS

Mouse Anti-FCRL2 Recombinant Antibody (CBT3584) (V2LY-0625-LY1153)

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Target: FCRL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3584
Application*: F
Datasheet SDS

Mouse Anti-FCRL2 Recombinant Antibody (CBXF-3306) (CBMAB-F0140-CQ)

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Target: FCRL2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-3306
Application*: E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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