FGF6

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation.

Full Name

Fibroblast Growth Factor 6

Research Area

Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration.

Biological Process

Angiogenesis Source: UniProtKB-KW
Animal organ morphogenesis Source: GO_Central
Cartilage condensation Source: Ensembl
Cell differentiation Source: GO_Central
Fibroblast growth factor receptor signaling pathway Source: MGI
Myoblast differentiation Source: Ensembl
Positive regulation of cell division Source: UniProtKB-KW
Positive regulation of cell population proliferation Source: MGI
Positive regulation of gene expression Source: GO_Central
Positive regulation of protein phosphorylation Source: GO_Central
Regulation of cell migration Source: GO_Central

Cellular Location

Extracellular space