Mouse Anti-FGF6 Recombinant Antibody (CBXF-1931) (CBMAB-F2782-CQ)

Name: Mouse Anti-FGF6 Recombinant Antibody (CBXF-1931)
SKU: CBMAB-F2782-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXF-1931

Application

WB, IP, IF, ELISA, IHC-P

Immunogen

Amino acids 171-198 at the C-terminus of human FGF-6.

Specificity

Human, Mouse, Rat, Horse, Dog, Pig

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500
ELISA	1:100-1:1,000
IHC-P	1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

Gelatin & PBS

Preservative

Sodium azide

Concentration

0.2 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Fibroblast Growth Factor 6

Introduction

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation.

Entrez Gene ID

2251

UniProt ID

P10767

Alternative Names

Fibroblast Growth Factor 6; Heparin Secretory-Transforming Protein 2; Heparin-Binding Growth Factor 6; HBGF-6; HSTF-2; FGF-6; HST-2; HST2; HSTF2;

Research Area

Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration.

Biological Process

Angiogenesis Source: UniProtKB-KW
Animal organ morphogenesis Source: GO_Central
Cartilage condensation Source: Ensembl
Cell differentiation Source: GO_Central
Fibroblast growth factor receptor signaling pathway Source: MGI
Myoblast differentiation Source: Ensembl
Positive regulation of cell division Source: UniProtKB-KW
Positive regulation of cell population proliferation Source: MGI
Positive regulation of gene expression Source: GO_Central
Positive regulation of protein phosphorylation Source: GO_Central
Regulation of cell migration Source: GO_Central

Cellular Location

Extracellular space

Zofkie, W., Southard, S. M., Braun, T., & Lepper, C. (2021). Fibroblast growth factor 6 regulates sizing of the muscle stem cell pool. Stem cell reports, 16(12), 2913-2927.

Zhi, Y., Sun, F., Cai, C., Li, H., Wang, K., Sun, J., ... & Cheng, R. (2021). LINC00265 promotes the viability, proliferation, and migration of bladder cancer cells via the miR-4677-3p/FGF6 axis. Human & Experimental Toxicology, 40(12_suppl), S434-S446.

Xu, Y., Tan, Q., Hu, P., & Yao, J. (2019). Characterization and expression analysis of FGF6 (fibroblast growth factor 6) genes of grass carp (Ctenopharyngodon idellus) reveal their regulation on muscle growth. Fish physiology and biochemistry, 45(5), 1649-1662.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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