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FGFR1OP2

FGFR1OP2 (FGFR1 Oncogene Partner 2) is a Protein Coding gene. Diseases associated with FGFR1OP2 include 8P11 Myeloproliferative Syndrome. Among its related pathways are VEGF Signaling Pathway and Signaling by FGFR2 in disease. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity. An important paralog of this gene is SIKE1.

Full Name

FGFR1 oncogene partner 2

Function

May be involved in wound healing pathway.

Biological Process

Response to wounding Source: GO_Central
Wound healing Source: Ensembl

Cellular Location

Cytoplasm

Involvement in disease

A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.

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Anti-FGFR1OP2 antibodies

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Mouse Anti-FGFR1OP2 Recombinant Antibody (CBXF-0614) (V2LY-0925-LY1681)

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Target: FGFR1OP2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXF-0614

Application*: E, WB

Mouse Anti-FGFR1OP2 Recombinant Antibody (CBXF-0613) (CBMAB-F0410-CQ)

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Target: FGFR1OP2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human, Mouse, Rat

Clone: CBXF-0613

Application*: WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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