FGFR1OP2

FGFR1OP2 (FGFR1 Oncogene Partner 2) is a Protein Coding gene. Diseases associated with FGFR1OP2 include 8P11 Myeloproliferative Syndrome. Among its related pathways are VEGF Signaling Pathway and Signaling by FGFR2 in disease. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity. An important paralog of this gene is SIKE1.
Full Name
FGFR1 oncogene partner 2
Function
May be involved in wound healing pathway.
Biological Process
Response to wounding Source: GO_Central
Wound healing Source: Ensembl
Cellular Location
Cytoplasm
Involvement in disease
A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.
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Anti-FGFR1OP2 antibodies

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Mouse Anti-FGFR1OP2 Recombinant Antibody (CBXF-0614) (V2LY-0925-LY1681)

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Target: FGFR1OP2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-0614
Application*: E, WB
Datasheet SDS

Mouse Anti-FGFR1OP2 Recombinant Antibody (CBXF-0613) (CBMAB-F0410-CQ)

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Target: FGFR1OP2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBXF-0613
Application*: WB
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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