FMN1

This gene belongs to the formin homology family and encodes a protein that has a role in the formation of adherens junction and the polymerization of linear actin cables. The homologous gene in mouse is associated with limb deformity. Alternatively spliced transcript variants have been found for this gene.

Full Name

formin 1

Function

Plays a role in the formation of adherens junction and the polymerization of linear actin cables.

Biological Process

Actin nucleation Source: InterPro
Forelimb morphogenesis Source: Ensembl
Gene expression Source: Ensembl
Hindlimb morphogenesis Source: Ensembl
Positive regulation of actin nucleation Source: Ensembl
Positive regulation of focal adhesion assembly Source: Ensembl
Skeletal system morphogenesis Source: Ensembl
Ureteric bud invasion Source: Ensembl

Cellular Location

Cell membrane; Cytoplasm; Nucleus; Adherens junction. Localization to the adherens junctions is alpha-catenin-dependent. Also localizes to F-actin bundles originating from adherens junctions and to microtubules (By similarity).

PTM

Phosphorylated on serine and possibly threonine residues.

Anti-FMN1 antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-FMN1 Recombinant Antibody (CBXF-1757) (CBMAB-F3292-CQ)

Datasheet

SDS

Target: FMN1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBXF-1757

Application*: WB, IP, IF, E

Mouse Anti-FMN1 Recombinant Antibody (4F4) (CBMAB-F1943-CQ)

Datasheet

SDS

Target: FMN1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4F4

Application*: E, IC, IF, WB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)