FPR3

FPR3 (Formyl Peptide Receptor 3) is a Protein Coding gene. Among its related pathways are Peptide ligand-binding receptors and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and N-formyl peptide receptor activity. An important paralog of this gene is FPR2.
Full Name
Formyl Peptide Receptor 3
Function
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Acts as a receptor for humanin (PubMed:15465011).
Biological Process
Chemotaxis Source: UniProtKB-KW
Complement receptor mediated signaling pathway Source: GO_Central
Inflammatory response Source: GO_Central
Phospholipase C-activating G protein-coupled receptor signaling pathway Source: GO_Central
Positive regulation of cytosolic calcium ion concentration Source: GO_Central
Signal transduction Source: ProtInc
Cellular Location
Cell membrane
Topology
Extracellular: 1-27
Helical: 28-50
Cytoplasmic: 51-61
Helical: 62-83
Extracellular: 84-100
Helical: 101-121
Cytoplasmic: 122-140
Helical: 141-162
Extracellular: 163-205
Helical: 206-226
Cytoplasmic: 227-242
Helical: 243-266
Extracellular: 267-286
Helical: 287-306
Cytoplasmic: 307-353
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Anti-FPR3 antibodies

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Target: FPR3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-2669
Application*: F
Target: FPR3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXF-3638
Application*: F
Target: FPR3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-1093
Application*: WB, F
Target: FPR3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3638
Application*: E, WB, IH, F
Target: FPR3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-1093
Application*: F
Target: FPR3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-2669
Application*: F, WB, IH
Target: FPR3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2758
Application*: IH, F
Target: FPR3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2482
Application*: IH, F
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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