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GABPA

This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.
Full Name
GA binding protein transcription factor subunit alpha
Function
Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene.
Biological Process
Blastocyst formation Source: Ensembl
Cell differentiation Source: GO_Central
Cellular response to dopamine Source: CAFA
Negative regulation of megakaryocyte differentiation Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: Ensembl
Positive regulation of gene expression Source: CAFA
Positive regulation of transcription by RNA polymerase II Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus

Anti-GABPA antibodies

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Target: GABPA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: 8C1B10
Application*: WB, IF, ELISA
Target: GABPA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1D6
Application*: IF, WB
Target: GABPA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 352C3a
Application*: DB
Target: GABPA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLG1-015
Application*: E, IF, WB
Target: GABPA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 13B334
Application*: E, WB
Target: GABPA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4B8-G6
Application*: E, IF, WB
Target: GABPA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5B6
Application*: E, IF, P, WB
Target: GABPA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5C8
Application*: IF, P, WB
Target: GABPA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 8C154
Application*: WB
Target: GABPA
Host: Mouse
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBLG1-3134
Application*: WB
Target: GABPA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLG1-430
Application*: IF, WB
Target: GABPA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBLG1-431
Application*: WB
Target: GABPA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-432
Application*: WB
Target: GABPA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2G3
Application*: IP, M
Target: GABPA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-0213
Application*: E, IF, WB
Target: GABPA
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: CBFYH-0214
Application*: WB, IP, IF, P, E
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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