GGPS1
This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
Full Name
geranylgeranyl diphosphate synthase 1
Function
Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.
Biological Process
Farnesyl diphosphate biosynthetic process Source: UniProtKB-UniPathway
Geranyl diphosphate biosynthetic process Source: UniProtKB-UniPathway
Geranylgeranyl diphosphate biosynthetic process Source: UniProtKB-UniPathway
Isoprenoid biosynthetic process Source: GO_Central
Isoprenoid metabolic process Source: UniProtKB
Geranyl diphosphate biosynthetic process Source: UniProtKB-UniPathway
Geranylgeranyl diphosphate biosynthetic process Source: UniProtKB-UniPathway
Isoprenoid biosynthetic process Source: GO_Central
Isoprenoid metabolic process Source: UniProtKB
Cellular Location
Cytoplasm
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Anti-GGPS1 antibodies
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CompareTarget: GGPS1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBLG1-1057
Application*: E, EC, WB
Target: GGPS1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBLG1-1055
Application*: E, WB
Target: GGPS1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBLG1-1054
Application*: WB
Target: GGPS1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBLG1-1053
Application*: SE, E, WB
Target: GGPS1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBLG1-2752
Application*: WB
Target: GGPS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-2751
Application*: WB
Target: GGPS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-2750
Application*: WB
Target: GGPS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3F9
Application*: P, WB
Target: GGPS1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYH-0339
Application*: E, WB
Target: GGPS1
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-300
Tag: His Tag
Target: GGPS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBLG1-1057
Application*: WB, IH
Target: GGPS1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: CBLG1-1055
Application*: WB
Target: GGPS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBLG1-1054
Application*: WB
Target: GGPS1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CBLG1-1053
Application*: WB, IP, IF, E
Target: GGPS1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLG1-2752
Application*: WB, IP, IF, E
Target: GGPS1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBLG1-2751
Application*: WB, E
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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