Mouse Anti-GGPS1 Recombinant Antibody (CBLG1-1053) (V2LY-1225-LY1172)

Name: Mouse Anti-GGPS1 Recombinant Antibody (CBLG1-1053)
SKU: V2LY-1225-LY1172
Rating: 5 (1 reviews)

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Published Data

Mouse Anti-GGPS1 Recombinant Antibody (CBLG1-1053) (V2LY-1225-LY1172) in WB

Western blotting on Ggpps using cerebellar samples across ages. ...View More

Cheng, Q., Wu, J., Xia, Y., Cheng, Q., Zhao, Y., Zhu, P., Zhang, W., Zhang, S., Zhang, L., Yuan, Y., Li, C., Chen, G., & Xue, B. (2023). Disruption of protein geranylgeranylation in the cerebellum causes cerebellar hypoplasia and ataxia via blocking granule cell progenitor proliferation. Molecular brain, 16(1), 24.

Mouse Anti-GGPS1 Recombinant Antibody (CBLG1-1053) (V2LY-1225-LY1172) in WB

Ggpps protein levels in livers from HFD-fed (12 h) C57BL/6J mice following the time-dependent FFA incubation of primary hepatocytes. The FFA mixture included oleic acid and palmitic acid at a ratio of 2:1 dissolved in BSA. (n = 3 mice per group). ...View More

Zhao, Y., Zhao, M. F., Jiang, S., Wu, J., Liu, J., Yuan, X. W., Shen, D., Zhang, J. Z., Zhou, N., He, J., Fang, L., Sun, X. T., Xue, B., & Li, C. J. (2020). Liver governs adipose remodelling via extracellular vesicles in response to lipid overload. Nature communications, 11(1), 719.

Mouse Anti-GGPS1 Recombinant Antibody (CBLG1-1053) (V2LY-1225-LY1172) in WB

Western blot analysis of GGPPS expression in lung adenocarcinoma (n = 6) and adjacent normal tissues (n = 6). ...View More

Wang, X., Xu, W., Zhan, P., Xu, T., Jin, J., Miu, Y., Zhou, Z., Zhu, Q., Wan, B., Xi, G., Ye, L., Liu, Y., Gao, J., Li, H., Lv, T., & Song, Y. (2018). Overexpression of geranylgeranyl diphosphate synthase contributes to tumour metastasis and correlates with poor prognosis of lung adenocarcinoma. Journal of cellular and molecular medicine, 22(4), 2177-2189.

Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBLG1-1053

Application

WB, IP, IF, ELISA

Immunogen

Full length of human GGPS1.

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

Application	Note
ELISA	1:100-1:1,000
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, gelatin

Preservative

Sodium azide

Concentration

0.2 mg/ml

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

geranylgeranyl diphosphate synthase 1

Entrez Gene ID

9453

UniProt ID

O95749

Function

Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.

Biological Process

Farnesyl diphosphate biosynthetic process Source: UniProtKB-UniPathway
Geranyl diphosphate biosynthetic process Source: UniProtKB-UniPathway
Geranylgeranyl diphosphate biosynthetic process Source: UniProtKB-UniPathway
Isoprenoid biosynthetic process Source: GO_Central
Isoprenoid metabolic process Source: UniProtKB

Cellular Location

Cytoplasm

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-GGPS1 Recombinant Antibody (CBLG1-1053) (CAT#: CBMAB-G3267-LY)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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