GLG1

GLG1 (Golgi Glycoprotein 1) is a Protein Coding gene. Diseases associated with GLG1 include Ecthyma and Pontocerebellar Hypoplasia, Type 2E. Among its related pathways are Cell surface interactions at the vascular wall and Apoptotic Pathways in Synovial Fibroblasts. Gene Ontology (GO) annotations related to this gene include signaling receptor binding.

Full Name

Golgi Glycoprotein 1

Function

Binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils).

Biological Process

Bone morphogenesis Source: Ensembl
Negative regulation of protein processing Source: Ensembl
Negative regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
Regulation of chondrocyte differentiation Source: Ensembl

Cellular Location

Golgi apparatus membrane; Golgi outpost; Microtubule organizing center. Golgi medial cisternae. Localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation.

Topology

Extracellular: 30-1145
Helical: 1146-1166
Cytoplasmic: 1167-1179

PTM

Fucosylation is essential for binding to E-selectin.By similarity
N-glycosylated. Contains sialic acid residues.By similarity

Anti-GLG1 antibodies

Mouse Anti-GLG1 Recombinant Antibody (858238) (CBMAB-G0511-LY)

Datasheet

SDS

Target: GLG1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: 858238

Application*: WB

Mouse Anti-GLG1 Recombinant Antibody (GLG1/970) (CBMAB-G0512-LY)

Datasheet

SDS

Target: GLG1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: GLG1/970

Application*: F

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)