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GLG1

GLG1 (Golgi Glycoprotein 1) is a Protein Coding gene. Diseases associated with GLG1 include Ecthyma and Pontocerebellar Hypoplasia, Type 2E. Among its related pathways are Cell surface interactions at the vascular wall and Apoptotic Pathways in Synovial Fibroblasts. Gene Ontology (GO) annotations related to this gene include signaling receptor binding.

Full Name

Golgi Glycoprotein 1

Function

Binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils).

Biological Process

Bone morphogenesis Source: Ensembl
Negative regulation of protein processing Source: Ensembl
Negative regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
Regulation of chondrocyte differentiation Source: Ensembl

Cellular Location

Golgi apparatus membrane; Golgi outpost; Microtubule organizing center. Golgi medial cisternae. Localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation.

Topology

Extracellular: 30-1145
Helical: 1146-1166
Cytoplasmic: 1167-1179

PTM

Fucosylation is essential for binding to E-selectin.By similarity
N-glycosylated. Contains sialic acid residues.By similarity

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Anti-GLG1 antibodies

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Mouse Anti-GLG1 Recombinant Antibody (GLG1/970) (CBMAB-G0512-LY)

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Target: GLG1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: GLG1/970

Application*: F

Mouse Anti-GLG1 Recombinant Antibody (858238) (CBMAB-G0511-LY)

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Target: GLG1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: 858238

Application*: WB

Mouse Anti-GLG1 Recombinant Antibody (1E6) (CBMAB-0410-YC)

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Target: GLI1

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 1E6

Application*: IH

Rabbit Anti-GLG1 Recombinant Antibody (CBFYH-0375) (V2LY-1225-LY1449)

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Target: GLG1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYH-0375

Application*: IH

Mouse Anti-GLG1 Recombinant Antibody (1A1) (V2LY-1225-LY1447)

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Target: GLG1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 1A1

Application*: P

Mouse Anti-GLG1 Recombinant Antibody (G0512) (V2LY-1225-LY1446)

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Target: GLG1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: G0512

Application*: WB, IF

Human Anti-GLG1 Recombinant Antibody (G0511) (V2LY-1225-LY1445)

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Target: GLG1

Host: Human

Antibody Isotype: IgG

Specificity: Human

Clone: G0511

Application*: E, F, in vivo

In Vivo Assay

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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