GLYAT

The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA's. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Full Name
glycine-N-acyltransferase
Function
Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.
Biological Process
Acyl-CoA metabolic process Source: ProtInc
Benzoyl-CoA metabolic process Source: UniProtKB
Glycine metabolic process Source: UniProtKB
Monocarboxylic acid metabolic process Source: UniProtKB
Response to toxic substance Source: ProtInc
Xenobiotic metabolic process Source: Reactome
Cellular Location
Mitochondrion
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Anti-GLYAT antibodies

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Mouse Anti-GLYAT Recombinant Antibody (CBLG1-1345) (CBMAB-G3975-LY)

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Target: GLYAT
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBLG1-1345
Application*: WB
Datasheet SDS

Mouse Anti-GLYAT Recombinant Antibody (CBLG1-2831) (CBMAB-G3974-LY)

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Target: GLYAT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-2831
Application*: WB
Datasheet SDS

Mouse Anti-GLYAT Recombinant Antibody (1A10) (CBMAB-G3971-LY)

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Target: GLYAT
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1A10
Application*: E, P, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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