Mouse Anti-GLYAT Recombinant Antibody (1A10) (CBMAB-G3971-LY)

Name: Mouse Anti-GLYAT Recombinant Antibody (1A10)
SKU: CBMAB-G3971-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

1A10

Application

ELISA, IHC-P, WB

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

glycine-N-acyltransferase

Introduction

The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA's. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Entrez Gene ID

10249

UniProt ID

Q6IB77

Alternative Names

Glycine-N-Acyltransferase; Aralkyl Acyl-CoA:Amino Acid N-Acyltransferase; Benzoyl-Coenzyme A:Glycine N-Acyltransferase; Acyl-CoA:Glycine N-Acyltransferase; Aralkyl Acyl-CoA N-Acyltransferase; Glycine N-Benzoyltransferase; EC 2.3.1.13; HRP-1(CLP);

Function

Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.

Biological Process

Acyl-CoA metabolic process Source: ProtInc
Benzoyl-CoA metabolic process Source: UniProtKB
Glycine metabolic process Source: UniProtKB
Monocarboxylic acid metabolic process Source: UniProtKB
Response to toxic substance Source: ProtInc
Xenobiotic metabolic process Source: Reactome

Cellular Location

Mitochondrion

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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