loading...

GPC4

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

Full Name

glypican 4

Function

Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system (By similarity).

Biological Process

Cell migration Source: GO_Central
Regulation of neurotransmitter receptor localization to postsynaptic specialization membrane Source: GO_Central
Regulation of presynapse assembly Source: GO_Central
Regulation of protein localization to membrane Source: GO_Central
Regulation of signal transduction Source: InterPro
Synaptic membrane adhesion Source: GO_Central
Wnt signaling pathway Source: UniProtKB

Cellular Location

Cell membrane
Secreted glypican-4: Extracellular space

Involvement in disease

Keipert syndrome (KPTS):
An X-linked recessive syndrome characterized by craniofacial and digital abnormalities. Clinical features include a prominent forehead, a flat midface, hypertelorism, a broad nose, downturned corners of mouth, and widening of all distal phalanges. Additional variable features are cognitive impairment and sensorineural deafness.

View more

Anti-GPC4 antibodies

+ Filters

Loading...

Mouse Anti-GPC4 Recombinant Antibody (4A3) (CBMAB-G4520-LY)

Compare

Target: GPC4

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 4A3

Application*: F, IF

Mouse Anti-GPC4 Recombinant Antibody (CBLG1-1601) (CBMAB-G4525-LY)

Compare

Target: GPC4

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBLG1-1601

Application*: E

Mouse Anti-GPC4 Recombinant Antibody (CBFYH-0437) (CBMAB-H1310-FY)

Compare

Target: GPC4

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYH-0437

Application*: E, F, IF, WB

Rabbit Anti-GPC4 Recombinant Antibody (CBLG1-1600) (V2LY-0226-LY708)

Compare

Target: GPC4

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse

Clone: CBLG1-1600

Application*: F, IF

More Infomation

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

online inquiry

Online Inquiry