GPR17

Full Name

G protein-coupled receptor 17

Function

Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.

Biological Process

G protein-coupled receptor signaling pathway Source: ProtInc
Positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling Pathway Source: GO_Central
Positive regulation of Rho protein signal transduction Source: GO_Central

Cellular Location

Cell membrane

Topology

Extracellular: 1-64
Helical: 65-85
Cytoplasmic: 86-92
Helical: 93-113
Extracellular: 114-133
Helical: 134-154
Cytoplasmic: 155-175
Helical: 176-196
Extracellular: 197-223
Helical: 224-244
Cytoplasmic: 245-260
Helical: 261-281
Extracellular: 282-308
Helical: 309-329
Cytoplasmic: 330-367

Anti-GPR17 antibodies

Rabbit Anti-GPR17 Recombinant Antibody (EG1390) (CBMAB-EN1669-LY)

Datasheet

SDS

Target: GPR17

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: EG1390

Application*: IF: 1:100~1:500 ELISA: 1:1000

Mouse Anti-GPR17 Recombinant Antibody (CBLG1-3203) (CBMAB-G4639-LY)

Datasheet

SDS

Target: GPR17

Host: Mouse

Antibody Isotype: IgG

Specificity: Mouse, Rat, Human

Clone: CBLG1-3203

Application*: WB

Mouse Anti-GPR17 Recombinant Antibody (3C10) (CBMAB-G4638-LY)

Datasheet

SDS

Target: GPR17

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 3C10

Application*: E, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)