GTF2F1

TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

Full Name

General Transcription Factor IIF Subunit 1

Function

TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

Biological Process

Negative regulation of protein binding Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: ComplexPortal
Positive regulation of transcription elongation from RNA polymerase II promoter Source: InterPro
Response to virus Source: UniProtKB
Transcription by RNA polymerase II Source: ProtInc
Transcription elongation from RNA polymerase II promoter Source: ComplexPortal
Transcription initiation from RNA polymerase II promoter Source: ARUK-UCL

Cellular Location

Nucleus

PTM

Phosphorylated on Ser and other residues by TAF1 and casein kinase II-like kinases.