Mouse Anti-GTF2F1 Recombinant Antibody (1D5) (CBMAB-G5688-LY)

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Basic Information

Host Animal
Mouse
Clone
1D5
Application
WB, IF, FC
Immunogen
Full length human recombinant protein of human GTF2F1.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, BSA, glycerol
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
General Transcription Factor IIF Subunit 1
Entrez Gene ID
UniProt ID
Alternative Names
BTF4; RAP74; TF2F1; TFIIF
Function
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.
Biological Process
Negative regulation of protein binding Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: ComplexPortal
Positive regulation of transcription elongation from RNA polymerase II promoter Source: InterPro
Response to virus Source: UniProtKB
Transcription by RNA polymerase II Source: ProtInc
Transcription elongation from RNA polymerase II promoter Source: ComplexPortal
Transcription initiation from RNA polymerase II promoter Source: ARUK-UCL
Cellular Location
Nucleus
PTM
Phosphorylated on Ser and other residues by TAF1 and casein kinase II-like kinases.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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