HILS1

This locus is the ortholog of a mouse protein-coding gene that displays characteristics of a linker histone and is expressed in nuclei of late maturing spermatids. The human locus is expressed; however, the open reading frame has been disrupted by a frameshift so it is unlikely to encode a functional protein.

Histone Linker H1 Domain, Spermatid-Specific 1 (Pseudogene)

DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa.

Chromatin remodeling Source: UniProtKB
Chromosome condensation Source: UniProtKB
Germ cell development Source: UniProtKB
Heterochromatin assembly Source: UniProtKB
Negative regulation of DNA recombination Source: GO_Central
Nucleosome assembly Source: InterPro
Nucleosome positioning Source: GO_Central
Regulation of transcription, DNA-templated Source: UniProtKB
Spermatogenesis Source: UniProtKB

Nucleus; Chromosome