HILS1

This locus is the ortholog of a mouse protein-coding gene that displays characteristics of a linker histone and is expressed in nuclei of late maturing spermatids. The human locus is expressed; however, the open reading frame has been disrupted by a frameshift so it is unlikely to encode a functional protein.

Full Name

Histone Linker H1 Domain, Spermatid-Specific 1 (Pseudogene)

Function

DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa.

Biological Process

Chromatin remodeling Source: UniProtKB
Chromosome condensation Source: UniProtKB
Germ cell development Source: UniProtKB
Heterochromatin assembly Source: UniProtKB
Negative regulation of DNA recombination Source: GO_Central
Nucleosome assembly Source: InterPro
Nucleosome positioning Source: GO_Central
Regulation of transcription, DNA-templated Source: UniProtKB
Spermatogenesis Source: UniProtKB

Cellular Location

Nucleus; Chromosome

Anti-HILS1 antibodies

Mouse Anti-HILS1 Recombinant Antibody (CBFYH-1106) (CBMAB-H2057-FY)

Datasheet

SDS

Target: HILS1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBFYH-1106

Application*: E, IF, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)