HSF2

The protein encoded by this gene belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription. Heat shock transcription factors activate heat-shock response genes under conditions of heat or other stresses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Full Name

heat shock transcription factor 2

Function

DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.

Biological Process

Positive regulation of transcription by RNA polymerase II Source: MGI
Regulation of transcription by RNA polymerase II Source: GO_Central
Spermatogenesis Source: Ensembl

Cellular Location

Nucleus; Cytoplasm. Cytoplasmic during normal growth and moves to the nucleus upon activation.

Anti-HSF2 antibodies

Rat Anti-HSF2 Recombinant Antibody (CBFYH-2058) (CBMAB-H3072-FY)

Datasheet

SDS

Target: HSF2

Host: Rat

Antibody Isotype: IgG1

Specificity: Cattle, Dog, Guinea pig, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep

Clone: CBFYH-2058

Application*: IF, IP, WB, IH

Mouse Anti-HSF2 Recombinant Antibody (CBFYH-2057) (CBMAB-H3071-FY)

Datasheet

SDS

Target: HSF2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYH-2057

Application*: WB

Rat Anti-HSF2 Recombinant Antibody (CBFYH-2056) (CBMAB-H3070-FY)

Datasheet

SDS

Target: HSF2

Host: Rat

Antibody Isotype: IgG1

Specificity: Mouse, Human, Monkey

Clone: CBFYH-2056

Application*: WB, IP, GS, IF

Mouse Anti-HSF2 Recombinant Antibody (CBFYH-2053) (CBMAB-H3067-FY)

Datasheet

SDS

Target: HSF2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYH-2053

Application*: DB

Rabbit Anti-HSF2 Recombinant Antibody (CBFYH-2045) (CBMAB-H3063-FY)

Datasheet

SDS

Target: HSF2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYH-2045

Application*: E, WB

Mouse Anti-HSF2 (AA 74-324) Recombinant Antibody (CBFYH-2044) (CBMAB-H3062-FY)

Datasheet

SDS

Target: HSF2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYH-2044

Application*: WB, IH

Rat Anti-HSF2 (AA 1-517) Recombinant Antibody (CBFYH-2043) (CBMAB-H3061-FY)

Datasheet

SDS

Target: HSF2

Host: Rat

Antibody Isotype: IgG1

Specificity: Human, Mouse, Monkey

Clone: CBFYH-2043

Application*: IF, IP, WB

Mouse Anti-HSF2 (AA 1-230) Monoclonal Antibody (CBFYH-3214) (CBMAB-H3060-FY)

Datasheet

SDS

Target: HSF2

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYH-3214

Application*: E, IF, WB

Rat Anti-HSF2 Recombinant Antibody (CBFYH-2051) (CBMAB-H0786-FY)

Datasheet

SDS

Target: HSF2

Host: Rat

Antibody Isotype: IgG1

Specificity: Mouse

Clone: CBFYH-2051

Application*: C, E, MS, IF, IP, WB

Rat Anti-HSF2 Recombinant Antibody (CBFYH-2052) (CBMAB-H0451-FY)

Datasheet

SDS

Target: HSF2

Host: Rat

Antibody Isotype: IgG

Specificity: Mouse, Rat, Sheep, Rabbit, Guinea pig, Hamster, Cattle, Dog, Human, Pig, Monkey

Clone: CBFYH-2052

Application*: WB

Rat Anti-HSF2 Recombinant Antibody (CBFYH-2048) (CBMAB-H0450-FY)

Datasheet

SDS

Target: HSF2

Host: Rat

Antibody Isotype: IgG1

Specificity: Mouse

Clone: CBFYH-2048

Application*: WB

Mouse Anti-HSF2 Recombinant Antibody (1F11-A3) (CBMAB-A4106-LY)

Datasheet

SDS

Target: HSF2

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 1F11-A3

Application*: WB, E

Rabbit Anti-HSF2 Recombinant Antibody (EG1567) (CBMAB-EN1869-LY)

Datasheet

SDS

Target: HSF2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: EG1567

Application*: WB: 1:500~1:1000 ELISA: 1:20000

Rat Anti-HSF2 Recombinant Antibody (A283) (CBMAB-AP9917LY)

Datasheet

SDS

Target: HSF2

Host: Rat

Antibody Isotype: IgG

Specificity: Cattle, Dog, Guinea pig, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep

Clone: A283

Application*: ICC/IF, AM, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)