IL1F10

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
Full Name
Interleukin 1 Family Member 10
Function
Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.
Biological Process
Cellular response to lipopolysaccharide Source: GO_Central
Cytokine-mediated signaling pathway Source: GO_Central
Inflammatory response Source: GO_Central
Inflammatory response to antigenic stimulus Source: GO_Central
Positive regulation of gene expression Source: GO_Central
Cellular Location
Cytoplasm; Secreted. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion.
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Anti-IL1F10 antibodies

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Mouse Anti-IL1F10 Recombinant Antibody (A517) (CBMAB-AP3774LY)

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Target: IL1F10
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A517
Application*: ELISA, IHC
Datasheet SDS

Mouse Anti-IL1F10 Recombinant Antibody (A516) (CBMAB-AP3773LY)

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Target: IL1F10
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: A516
Application*: IHC
Datasheet SDS

Mouse Anti-IL1F10 Recombinant Antibody (A515) (CBMAB-AP10855LY)

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Target: IL1F10
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A515
Application*: ELISA, WB
Datasheet SDS

Mouse Anti-IL1F10 Recombinant Antibody (CF228) (CBMAB-FT261LY)

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Target: IL1F10
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CF228
Application*: ELISA, WB
Datasheet SDS

Mouse Anti-IL1F10 Recombinant Antibody (CB274A) (CBMAB-CA274LY)

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Target: IL1F10
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB274A
Application*: ELISA, IHC
Datasheet SDS

Mouse Anti-IL1F10 Recombinant Antibody (2A2B3) (CBMAB-R4274-CN)

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Target: IL1F10
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2A2B3
Application*: E, IH
Datasheet SDS

Rat Anti-IL1F10 Recombinant Antibody (CBYY-I1351) (CBMAB-I2521-YY)

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Target: IL1F10
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-I1351
Application*: E, WB
Datasheet SDS

Rat Anti-IL1F10 Recombinant Antibody (798036R) (CBMAB-I1646-YY)

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Target: IL1F10
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 798036R
Application*: WB, F
Datasheet SDS

Rat Anti-IL1F10 Recombinant Antibody (CBYY-I0741) (CBMAB-I1645-YY)

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Target: IL1F10
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYY-I0741
Application*: WB, F, MC
Datasheet SDS

Mouse Anti-IL1F10 Recombinant Antibody (CBYY-I0013) (CBMAB-I0024-YY)

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Target: IL1F10
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYY-I0013
Application*: E, F, P, IP, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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