Sign in or Register   Sign in or Register
  |  

Mouse Anti-IL1F10 Recombinant Antibody (2A2B3) (CBMAB-R4274-CN)

This product is a mouse antibody that recognizes IL1F10 of human. The antibody 2A2B3 can be used for immunoassay techniques such as: ELISA, IHC.
See all IL1F10 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2A2B3
Antibody Isotype
IgG1
Application
ELISA, IHC

Basic Information

Immunogen
Recombinant Human IL1F10 protein
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
0.01 M PBS, PH 7.4, 50% Glycerol
Preservative
0.03% Proclin 300
Purity
>95%
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target

Full Name
Interleukin 1 Family Member 10
Introduction
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
Entrez Gene ID
84639
UniProt ID
Q8WWZ1
Alternative Names
Interleukin 1 Family Member 10
Function
Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.
Biological Process
Cellular response to lipopolysaccharide Source: GO_Central
Cytokine-mediated signaling pathway Source: GO_Central
Inflammatory response Source: GO_Central
Inflammatory response to antigenic stimulus Source: GO_Central
Positive regulation of gene expression Source: GO_Central
Cellular Location
Cytoplasm; Secreted. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-IL1F10 Recombinant Antibody (2A2B3)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare