INS1
Ins1 is a 'defective gene' relative to Ins2, and that the mouse lines created provide a novel model of sex-dimorphic insulin-deficient diabetes.
Full Name
insulin 1
Function
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
Biological Process
Glucose homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Glucose metabolic processIEA:UniProtKB-KW
Positive regulation of protein secretionManual Assertion Based On ExperimentIBA:GO_Central
Response to cAMPManual Assertion Based On ExperimentIEP:RGD
Response to cytokineManual Assertion Based On ExperimentIEP:RGD
Response to organic substanceManual Assertion Based On ExperimentIEP:RGD
Response to peptide hormoneManual Assertion Based On ExperimentIEP:RGD
Glucose metabolic processIEA:UniProtKB-KW
Positive regulation of protein secretionManual Assertion Based On ExperimentIBA:GO_Central
Response to cAMPManual Assertion Based On ExperimentIEP:RGD
Response to cytokineManual Assertion Based On ExperimentIEP:RGD
Response to organic substanceManual Assertion Based On ExperimentIEP:RGD
Response to peptide hormoneManual Assertion Based On ExperimentIEP:RGD
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Anti-INS1 antibodies
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CompareTarget: INS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBFYC-2785
Application*: E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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