INV

Invected (Inv) is a homeodomain transcription factor that is closely related to, co-expressed with, and functionally redundant with en. Although dispensable in the laboratory, Inv is a transcriptional repressor important for segmentation in the embryo and formation of the posterior compartment in imaginal discs

Full Name

Invected

Function

Engrailed (en) and invected (inv) are functionally redundant transcription factors in neuronal precursor cell NB5-3 specification. Inv is unable to substitute for en in other regulatory processes such as maintaining gsb expression in the neuroectoderm after stage 10 of embryogenesis. Maintenance of gsb expression in row 5 of the neuroectoderm involves an as yet unidentified short range signaling molecule.

Biological Process

Compartment pattern specificationManual Assertion Based On ExperimentTAS:FlyBase
Defense response to fungusManual Assertion Based On ExperimentIMP:FlyBase
Imaginal disc-derived wing vein specificationManual Assertion Based On ExperimentIMP:FlyBase
Neuroblast fate determinationManual Assertion Based On ExperimentIGI:FlyBase
Neuron differentiationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Wing disc anterior/posterior pattern formationManual Assertion Based On ExperimentTAS:FlyBase

Cellular Location

Nucleus