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Mouse Anti-INV Recombinant Antibody (4D9) (CBMAB-0220-CN)

This product is a mouse antibody that recognizes INV of Drosophila. The antibody 4D9 can be used for immunoassay techniques such as: ChIP, BL, IF, IHC, IP, WB.
See all INV antibodies

Summary

Host Animal
Mouse
Specificity
Common fruit fly, Beetle, Chicken, Crayfish, Fish, Grasshopper, Lobster, Mollusc, Worm, Xenopus, Zebrafish
Clone
4D9
Antibody Isotype
IgG1
Application
ChIP, Blocking, IF, IHC, IP, WB

Basic Information

Immunogen
Invected (C-terminal two-thirds of the invected protein); recombinant.
Specificity
Common fruit fly, Beetle, Chicken, Crayfish, Fish, Grasshopper, Lobster, Mollusc, Worm, Xenopus, Zebrafish
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Invected
Introduction
Invected (Inv) is a homeodomain transcription factor that is closely related to, co-expressed with, and functionally redundant with en. Although dispensable in the laboratory, Inv is a transcriptional repressor important for segmentation in the embryo and formation of the posterior compartment in imaginal discs
Entrez Gene ID
36239
UniProt ID
P05527
Alternative Names
CG17835; Dmel\CG17835; Engrailed/Invected; er; in; Inv; INV; IV
Function
Engrailed (en) and invected (inv) are functionally redundant transcription factors in neuronal precursor cell NB5-3 specification. Inv is unable to substitute for en in other regulatory processes such as maintaining gsb expression in the neuroectoderm after stage 10 of embryogenesis. Maintenance of gsb expression in row 5 of the neuroectoderm involves an as yet unidentified short range signaling molecule.
Biological Process
Compartment pattern specificationManual Assertion Based On ExperimentTAS:FlyBase
Defense response to fungusManual Assertion Based On ExperimentIMP:FlyBase
Imaginal disc-derived wing vein specificationManual Assertion Based On ExperimentIMP:FlyBase
Neuroblast fate determinationManual Assertion Based On ExperimentIGI:FlyBase
Neuron differentiationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Wing disc anterior/posterior pattern formationManual Assertion Based On ExperimentTAS:FlyBase
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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