KCNIP1

This gene encodes a member of the family of cytosolic voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the neuronal calcium sensor (NCS) family of the calcium binding EF-hand proteins. They associate with Kv4 alpha subunits to form native Kv4 channel complexes. The encoded protein may regulate rapidly inactivating (A-type) currents, and hence neuronal membrane excitability, in response to changes in the concentration of intracellular calcium. Alternative splicing results in multiple transcript variants encoding different isoforms.
Full Name
potassium voltage-gated channel interacting protein 1
Function
Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Regulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Increases the presence of KCND2 at the cell surface.
Biological Process
Regulation of potassium ion transmembrane transportManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cell membrane; Cytoplasm; Cell projection, dendrite
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Anti-KCNIP1 antibodies

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Rabbit Anti-KCNIP1 Recombinant Antibody (CBLY1-050) (CBMAB-K0538-LY)

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Target: KCNIP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBLY1-050
Application*: WB, IP, F
Datasheet SDS

Mouse Anti-KCNIP1 Recombinant Antibody (S55-82) (CBMAB-K0545-LY)

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Target: KCNIP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rat, Mouse, Human
Clone: S55-82
Application*: C, IF, IP, WB
Datasheet SDS

Mouse Anti-KCNIP1 Recombinant Antibody (S55-7) (CBMAB-K0544-LY)

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Target: KCNIP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Human, Mouse
Clone: S55-7
Application*: IH, C, IP
Datasheet SDS

Mouse Anti-KCNIP1 Recombinant Antibody (3D9) (CBMAB-K0541-LY)

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Target: KCNIP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3D9
Application*: E, WB
Datasheet SDS

Mouse Anti-KCNIP1 Recombinant Antibody (3D6C1) (CBMAB-K0540-LY)

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Target: KCNIP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3D6C1
Application*: E, WB, IH
Datasheet SDS

Mouse Anti-KCNIP1 Recombinant Antibody (11E2) (CBMAB-K0539-LY)

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Target: KCNIP1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 11E2
Application*: WB
Datasheet SDS

Rabbit Anti-KCNIP1 Recombinant Antibody (EG1742) (CBMAB-EN2081-LY)

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Target: KCNIP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EG1742
Application*: IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:20000
Datasheet SDS

Mouse Anti-KCNIP1 Recombinant Antibody (A735) (CBMAB-AP10984LY)

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Target: KCNIP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A735
Application*: ELISA, IHC, WB
Datasheet SDS

Mouse Anti-KCNIP1 (AA 20-100) Recombinant Antibody (CBYY-1076) (CBMAB-1080-YY)

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Target: KCNIP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-1076
Application*: WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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