KLK5

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]
Full Name
kallikrein-related peptidase 5
Function
May be involved in desquamation.
Biological Process
AmelogenesisManual Assertion Based On ExperimentIBA:GO_Central
CornificationTAS:Reactome
Epidermis developmentManual Assertion Based On ExperimentTAS:ProtInc
Extracellular matrix disassemblyManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of antibacterial peptide productionManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Secreted
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Anti-KLK5 antibodies

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Rabbit Anti-KLK5 Recombinant Antibody (CBLY1-123) (CBMAB-K1298-LY)

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Target: KLK5
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Human
Clone: CBLY1-123
Application*: WB, F, IC/IF
Datasheet SDS

Rat Anti-KLK5 Recombinant Antibody (880036) (CBMAB-K1303-LY)

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Target: KLK5
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: 880036
Application*: WB, IH
Datasheet SDS

Mouse Anti-KLK5 Recombinant Antibody (4D27) (CBMAB-K1302-LY)

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Target: KLK5
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 4D27
Application*: WB
Datasheet SDS

Mouse Anti-KLK5 Recombinant Antibody (3H3) (CBMAB-K1301-LY)

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Target: KLK5
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3H3
Application*: E
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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