KTN1

This gene encodes an integral membrane protein that is a member of the kinectin protein family. The encoded protein is primarily localized to the endoplasmic reticulum membrane. This protein binds kinesin and may be involved in intracellular organelle motility. This protein also binds translation elongation factor-delta and may be involved in the assembly of the elongation factor-1 complex. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Aug 2012]

Kinectin 1

Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin.

Microtubule-based movement1 PublicationNAS:ProtInc
Protein transportIEA:InterPro

Endoplasmic reticulum membrane
Vesicle membrane protein anchored to the endoplasmic reticulum.

Cytoplasmic: 1-6
Helical: 7-29
Lumenal: 30-1357